NASA's Marshall Space Flight Center (MSFC) is the lead center for Materials Science Microgravity Research. The Materials Science Research Facility (MSRF) is a key development effort underway at MSFC. The MSRF will be the primary facility for microgravity materials science research on board the International Space Station (ISS) and will implement the NASA Materials Science Microgravity Research Program. It will operate in the U.S. Laboratory Module and support U. S. Microgravity Materials Science Investigations. This facility is being designed to maintain the momentum of the U.S. role in microgravity materials science and support NASA's Human Exploration and Development of Space (HEDS) Enterprise goals and objectives for Materials Science. The MSRF as currently envisioned will consist of three Materials Science Research Racks (MSRR), which will be deployed to the International Space Station (ISS) in phases, Each rack is being designed to accommodate various Experiment Modules, which comprise processing facilities for peer selected Materials Science experiments. Phased deployment will enable early opportunities for the U.S. and International Partners, and support the timely incorporation of technology updates to the Experiment Modules and sensor devices.